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Friday, July 2, 2010

Total Pancreatectomy

  • Total pancreatectomy for pancreatic cancer is usually not recommended as the endocrine and exocrine functions of the pancreas are totally lost which result in severe metabolic disturbances.
  • Total pancreatectomy may prevent pancreatic fistulas and provide a radical eradication of the tumor.
  • The median survival rates are reported to be shorter after total pancreatectomy than after pancreaticoduodenectomy.
  • Total pancreatectomy is considered in a few selected patients, e.g. patients with positive resection margins in frozen sections (e.g. IPMN) or tumors not resectable with partial pancreactectomy.
  • If total pancreatectomy is opted, retaining the pylorus improves the post surgical outcome.

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