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Tuesday, April 14, 2009

Obesity and Liver Disease

With improvement in economic status, food availability and increased western dietary habits, obesity is being increasingly recognized in Indian children.

Obesity is an established risk factor for:
• Cardiovascular disease
• Diabetes mellitus
• Liver disease

Liver is involved in 10-20% of children with obesity and severity of involvement increases with degree of obesity. Liver involvement in obese children includes:

• Liver enlargement with deposition of fat in liver cells (fatty liver / steatosis )
• Fatty liver with inflammation (steato-hepatitis)
• Steatohepatitis in due course of time can rarely progress to cirrhosis and liver failure.

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